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Palliative Care

The St. Jude Global Palliative Care Program attends to the suffering of children diagnosed with catastrophic illness and their families, regardless of diagnosis, prognosis or location. Our program does this through high-quality, evidence-based medicine and the art of healing through compassionate and empathetic care. 


Our program focuses on quality of life by promoting the dignity and comfort of patients and their families, addressing their physical, psychological, social and spiritual suffering.


Program Initiatives 


The Global Palliative Care Program is working to define the current state of palliative care in underserved communities worldwide and to drive interventions to relieve the suffering of patients and their families. This is done, in collaboration with our global partners, through culturally sensitive projects based on the four pillars of the program: research, education, capacity building and advocacy. 


Examples of this work include: 




We support research initiatives that aim to describe the current state of palliative care for children globally and the implementation of high-quality, evidence-based interventions in pediatric palliative care. 

  • ADAPT: The Assessing Doctors’ Attitudes on Palliative Treatment (ADAPT) study identifies physician access, barriers, knowledge and perceptions on palliative care integration for children diagnosed with cancer, as outlined by the World Health Organization (WHO) guide in 2018.  
    • In 2019, we conducted the ADAPT study across 11 countries in the Euro region (formerly the Eurasia region), obtaining a median country response rate of 60% (range: 15%–94%). We published our ADAPT Eurasia study findings in two publications in Cancer Journal.  
    • Based on the success of the ADAPT-Euro study, our group plans to conduct this study across all global regions. It has completed the ADAPT study in Latin America, conducting the study across 18 countries, with an overall response rate of 51.4% (23.7%-100%). We have published our ADAPT Latin America study findings in JAMA Network Open. 
    • Currently, the ADAPT study is being conducted in the Asia Pacific, Western Europe and Eastern Mediterranean regions, with plans to conduct the study in China and Sub-Saharan Africa.  
    • The expansion of the ADAPT study will make it possible to describe the global perspective of health care professionals regarding palliative care in childhood cancer and to create strategies adapted to each region's needs. 
  • CATALYST Study: The Clinician Approach to Choosing Therapy in LMICs for Young Patients With Cancer at the Start of Treatment Study aims to investigate the variables influencing physicians’ upfront treatment decision-making in LMICs​ (low- and middle-income countries).

    An estimated 90% of pediatric cancer diagnoses occur in low- and middle-income countries (LMICs), with many children presenting with advanced or incurable cancer at the time of diagnosis. Why, when or how physicians in LMICs make decisions about offering curative versus noncurative treatments to these children is poorly understood. The CATALYST study uses qualitative methodology to understand this decision-making process better.




The St. Jude Global Palliative Care Program has built internal and external training opportunities to support multidisciplinary clinicians in providing palliative care for children diagnosed with catastrophic illnesses. 

  • Opportunities at St. Jude Children’s Research Hospital: Our program offers observational rotations, palliative care research internships and a global fellowship in palliative care on campus. Each year, the program holds the Global Academy in Palliative Care in Memphis, which includes Education in Palliative and End-of-Life Care (EPEC) Pediatrics training, among other training opportunities. In 2022, the Global Academy had local and international facilitators and included 42 multidisciplinary health professionals from 29 countries. 
  • External Opportunities for Education and Training: Externally, the Global Palliative Care Program offers multiple educational workshops on general and specific palliative care topics such as pain and symptom management, end-of-life care and grief and bereavement support. Additionally, we have supported scholarships to enable individuals from LMICs to participate in EPEC Pediatrics training. This training is now held in different parts of the world, in multiple languages​​ and adapted to regional needs. These course offerings include online and in-person training in the principles of palliative care for pediatric patients. Between 2021 and 2022, EPEC Pediatrics courses were held in Latin America, Europe and Africa. In that time, our program awarded 230 scholarships to health professionals from 56 countries for various virtual and in-person training events.


Capacity Building 


Through patient-centered initiatives, we develop projects that strengthen palliative care skills for practical application and improvement in direct patient care. 

  • Adapted Resource and Implementation Application (ARIA) Guide: In a collaboration between St. Jude Global and the International Society of Paediatric Oncology (SIOP), the ARIA project involves developing a shared online platform for hosting detailed Adapted Management Guidelines for the diagnosis, treatment and supportive care of children diagnosed with cancer. ARIA integrates the revised SIOP Pediatric Oncology in Developing Countries (PODC) adapted treatment regimens to produce practical treatment guidance. Our team and international multidisciplinary collaborators are leading the palliative care component of the ARIA guidelines. 
  • Global Comfort Promise Package: The Global Comfort Promise is a St. Jude Global Procedural Pain Package that aims to reduce procedural pain in children diagnosed with cancer. We are piloting this quality improvement project in four countries — Brazil, Peru, the Philippines and South Africa — with excellent results. By 2023 the project is expected to enter the expansion phase, with 15 to 20 more sites worldwide.  
  • PrOTECT (Pediatric Oncology Tool for End-of-Life Care Treatment): PrOTECT will define a set of measures to assess the quality of end-of-life care for children diagnosed with cancer in LMICs. The tool is currently under development, utilizing modified Delphi and discrete choice experimental methodology, with an expected completion date of spring 2023 and plans to pilot the tool in summer 2023. 




We advocate for positive change through our research and collaborations with WHO, the Pan American Health Organization (PAHO), the International Children’s Palliative Care Network (ICPCN), the Worldwide Hospice Palliative Care Alliance (WHPCA) and many others.  


The synergy created between our four pillars will result in a comprehensive response to relieve the suffering of underserved communities worldwide. 


Our Team


Michael McNeil, MD, MPH

Director, Global Palliative Care Program

Full Bio


Marta Salek, MD, MPH

Clinical Education and Training


Ximena Garcia, MD

Project Coordinator, Global Palliative Care Program


Doralina Anghelescu, MD

Consultant, Global Palliative Care Program




To learn about the Palliative Care Program, email